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Reaction Details
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Targetnuclear receptor subfamily 5 group A member 2 isoform 2
LigandBDBM95519
Substrate/Competitorn/a
IC50>3986±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article
 
nuclear receptor subfamily 5 group A member 2 isoform 2
Name:Liver Receptor Homolog 1
Synonyms:Alpha-1-fetoprotein transcription factor | B1-binding factor | CYP7A promoter-binding factor | Hepatocytic transcription factor | LRH-1 | Nuclear receptor subfamily 5 group A member 2 | hB1F
Type:Nuclear Hormone Receptor
Mol. Mass.:61341.37
Organism:Homo sapiens (Human)
Description:n/a
Residue:541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQG
QMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRY
TCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQ
QKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPF
VTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPAS
IPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWA
RSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQA
GATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAA
LLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKR
A
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  Blast E-value cutoff:
BDBM95519
NameBDBM95519
Synonyms:MLS000694878 | N-({[(2-fluorobenzyl)oxy]imino}methyl)-4-methoxy-2-phenoxynicotinamide | N-[[(2-fluorobenzyl)oxyamino]methylene]-4-methoxy-2-phenoxy-nicotinamide | N-[[(2-fluorophenyl)methoxyamino]methylidene]-4-methoxy-2-phenoxy-3-pyridinecarboxamide | N-[[(2-fluorophenyl)methoxyamino]methylidene]-4-methoxy-2-phenoxy-pyridine-3-carboxamide | N-[[(2-fluorophenyl)methoxyamino]methylidene]-4-methoxy-2-phenoxypyridine-3-carboxamide | SMR000334758 | cid_5191161
TypeSmall organic molecule
Emp. Form.C21H18FN3O4
Mol. Mass.395.3837
SMILESCOc1ccnc(Oc2ccccc2)c1C(=O)NC=NOCc1ccccc1F |w:19.21|
Structure
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n/a