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Reaction Details
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Targetnuclear receptor subfamily 5 group A member 2 isoform 2
LigandBDBM95567
Substrate/Competitorn/a
IC50 450.15±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article
 
nuclear receptor subfamily 5 group A member 2 isoform 2
Name:Liver Receptor Homolog 1
Synonyms:Alpha-1-fetoprotein transcription factor | B1-binding factor | CYP7A promoter-binding factor | Hepatocytic transcription factor | LRH-1 | Nuclear receptor subfamily 5 group A member 2 | hB1F
Type:Nuclear Hormone Receptor
Mol. Mass.:61341.37
Organism:Homo sapiens (Human)
Description:n/a
Residue:541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQG
QMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRY
TCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQ
QKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPF
VTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPAS
IPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWA
RSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQA
GATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAA
LLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKR
A
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BDBM95567
NameBDBM95567
Synonyms:4-Chloro-1-methyl-1H-pyrazole-3-carboxylic acid (4-sulfamoyl-phenylcarbamoyl)-methyl ester | 4-chloro-1-methyl-3-pyrazolecarboxylic acid [2-oxo-2-(4-sulfamoylanilino)ethyl] ester | 4-chloro-1-methyl-pyrazole-3-carboxylic acid [2-keto-2-(4-sulfamoylanilino)ethyl] ester | MLS001218058 | SMR000602485 | [2-oxidanylidene-2-[(4-sulfamoylphenyl)amino]ethyl] 4-chloranyl-1-methyl-pyrazole-3-carboxylate | [2-oxo-2-(4-sulfamoylanilino)ethyl] 4-chloro-1-methylpyrazole-3-carboxylate | cid_5153388
TypeSmall organic molecule
Emp. Form.C13H13ClN4O5S
Mol. Mass.372.784
SMILESCn1cc(Cl)c(n1)C(=O)OCC(=O)Nc1ccc(cc1)S(N)(=O)=O
Structure
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n/a