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Reaction Details
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Targetnuclear receptor subfamily 5 group A member 2 isoform 2
LigandBDBM95586
Substrate/Competitorn/a
IC50>3986±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article
 
nuclear receptor subfamily 5 group A member 2 isoform 2
Name:Liver Receptor Homolog 1
Synonyms:Alpha-1-fetoprotein transcription factor | B1-binding factor | CYP7A promoter-binding factor | Hepatocytic transcription factor | LRH-1 | Nuclear receptor subfamily 5 group A member 2 | hB1F
Type:Nuclear Hormone Receptor
Mol. Mass.:61341.37
Organism:Homo sapiens (Human)
Description:n/a
Residue:541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQG
QMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRY
TCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQ
QKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPF
VTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPAS
IPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWA
RSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQA
GATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAA
LLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKR
A
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  Blast E-value cutoff:
BDBM95586
NameBDBM95586
Synonyms:2-(2-keto-7-methyl-4-propyl-chromen-5-yl)oxy-N-(2-pyridyl)acetamide | 2-(7-methyl-2-oxidanylidene-4-propyl-chromen-5-yl)oxy-N-pyridin-2-yl-ethanamide | 2-(7-methyl-2-oxo-4-propylchromen-5-yl)oxy-N-pyridin-2-ylacetamide | 2-[(7-methyl-2-oxo-4-propyl-1-benzopyran-5-yl)oxy]-N-(2-pyridinyl)acetamide | MLS001160382 | SMR000652652 | cid_8034762
TypeSmall organic molecule
Emp. Form.C20H20N2O4
Mol. Mass.352.3838
SMILESCCCc1cc(=O)oc2cc(C)cc(OCC(=O)Nc3ccccn3)c12
Structure
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n/a