BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Targetnuclear receptor subfamily 5 group A member 2 isoform 2
LigandBDBM95653
Substrate/Competitorn/a
IC50>3984±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article
 
nuclear receptor subfamily 5 group A member 2 isoform 2
Name:Liver Receptor Homolog 1
Synonyms:Alpha-1-fetoprotein transcription factor | B1-binding factor | CYP7A promoter-binding factor | Hepatocytic transcription factor | LRH-1 | Nuclear receptor subfamily 5 group A member 2 | hB1F
Type:Nuclear Hormone Receptor
Mol. Mass.:61341.37
Organism:Homo sapiens (Human)
Description:n/a
Residue:541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQG
QMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRY
TCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQ
QKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPF
VTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPAS
IPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWA
RSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQA
GATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAA
LLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKR
A
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM95653
NameBDBM95653
Synonyms:1-oxido-3-pyridin-1-iumcarboxylic acid [2-(2-chloro-4-nitroanilino)-2-oxoethyl] ester | 1-oxidopyridin-1-ium-3-carboxylic acid [2-(2-chloro-4-nitro-anilino)-2-keto-ethyl] ester | MLS002170576 | SMR001250891 | [2-(2-chloro-4-nitroanilino)-2-oxoethyl] 1-oxidopyridin-1-ium-3-carboxylate | [2-[(2-chloranyl-4-nitro-phenyl)amino]-2-oxidanylidene-ethyl] 1-oxidanidylpyridin-1-ium-3-carboxylate | cid_3659548
TypeSmall organic molecule
Emp. Form.C14H10ClN3O6
Mol. Mass.351.699
SMILES[O-][N+](=O)c1ccc(NC(=O)COC(=O)c2ccc[n+]([O-])c2)c(Cl)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a