Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM30786
Substrate
n/a
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM30786
Synonyms:
1-(4-chlorobenzyl)-N-(2-furfuryl)-2-imino-5-keto-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 1-[(4-chlorophenyl)methyl]-N-(2-furanylmethyl)-2-imino-5-oxo-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide | 1-[(4-chlorophenyl)methyl]-N-(furan-2-ylmethyl)-2-imino-5-oxodipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 2-azanylidene-1-[(4-chlorophenyl)methyl]-N-(furan-2-ylmethyl)-5-oxidanylidene-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | MLS000083283 | SMR000047818 | cid_666486
Type:
Small organic molecule
Emp. Form.:
C24H18ClN5O3
Mol. Mass.:
459.884
SMILES:
Clc1ccc(Cn2c3nc4ccccn4c(=O)c3cc(C(=O)NCc3ccco3)c2=N)cc1
Structure:
Search PDB for entries with ligand similarity: