Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM95034
Substrate
n/a
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM95034
Synonyms:
1-Ethyl-6-fluoro-7-[4-(4-fluoro-benzoylaminocarbothioyl)-piperazin-1-yl]-4-oxo-1,4-dihydro-quinoline-3-c arboxylic acid | 1-ethyl-6-fluoranyl-7-[4-[(4-fluorophenyl)carbonylcarbamothioyl]piperazin-1-yl]-4-oxidanylidene-quinoline-3-carboxylic acid | 1-ethyl-6-fluoro-7-[4-[(4-fluorobenzoyl)carbamothioyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid | 1-ethyl-6-fluoro-7-[4-[(4-fluorobenzoyl)thiocarbamoyl]piperazino]-4-keto-quinoline-3-carboxylic acid | 1-ethyl-6-fluoro-7-[4-[[[(4-fluorophenyl)-oxomethyl]amino]-sulfanylidenemethyl]-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid | MLS000777983 | SMR000414377 | cid_1920133
Type:
Small organic molecule
Emp. Form.:
C24H22F2N4O4S
Mol. Mass.:
500.518
SMILES:
CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(CC1)C(=S)NC(=O)c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: