Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94988
Substrate
n/a
IC50
8330±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94988
Synonyms:
MLS000830187 | N-(4-keto-7-methyl-thieno[3,2-d][1,3]thiazin-2-yl)thiophene-2-carboxamide | N-(7-methyl-4-oxidanylidene-thieno[3,2-d][1,3]thiazin-2-yl)thiophene-2-carboxamide | N-(7-methyl-4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-2-thiophenecarboxamide | N-(7-methyl-4-oxo-4H-thieno[3,2-d][1,3]thiazin-2-yl)thiophene-2-carboxamide | N-(7-methyl-4-oxothieno[3,2-d][1,3]thiazin-2-yl)thiophene-2-carboxamide | SMR000458108 | cid_2810073
Type:
Small organic molecule
Emp. Form.:
C12H8N2O2S3
Mol. Mass.:
308.399
SMILES:
Cc1csc2c1nc(NC(=O)c1cccs1)sc2=O
Structure:
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