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TargetFructose-1,6-bisphosphate aldolase (FBA)
LigandBDBM96138
Substrate/Competitorn/a
IC50>369.89±n/a nM
Citation PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis PubChem Bioassay(2013)[AID]
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Fructose-1,6-bisphosphate aldolase (FBA)
Name:Fructose-1,6-bisphosphate aldolase (FBA)
Synonyms:FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba
Type:Protein
Mol. Mass.:36539.01
Organism:Mycobacterium tuberculosis (strain H37Rv)
Description:P9WQA3
Residue:344
Sequence:
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFG
SGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKG
GNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKL
YTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGL
PADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLK
VDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM96138
NameBDBM96138
Synonyms:4-[(6-methoxyfuro[2,3-b]quinoline-2-carbonyl)amino]piperidine-1-carboxylic acid ethyl ester | 4-[[(6-methoxy-2-furo[2,3-b]quinolinyl)-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester | MLS000091909 | SMR000026433 | cid_3239341 | ethyl 4-[(6-methoxyfuro[2,3-b]quinolin-2-yl)carbonylamino]piperidine-1-carboxylate | ethyl 4-[(6-methoxyfuro[2,3-b]quinoline-2-carbonyl)amino]piperidine-1-carboxylate | ethyl 4-{[(6-methoxyfuro[2,3-b]quinolin-2-yl)carbonyl]amino}piperidine-1-carboxylate
TypeSmall organic molecule
Emp. Form.C21H23N3O5
Mol. Mass.397.4244
SMILESCCOC(=O)N1CCC(CC1)NC(=O)c1cc2cc3cc(OC)ccc3nc2o1
Structure
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n/a