Reaction Details Report a problem with these data
Target
Fructose-bisphosphate aldolase
Ligand
BDBM96143
Substrate
n/a
IC50
>1111±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis PubChem Bioassay (2013)[AID] 
Target
Name:
Fructose-bisphosphate aldolase
Synonyms:
ALF_MYCTU | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-1,6-bisphosphate aldolase (FBA) | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba | fba
Type:
Protein
Mol. Mass.:
36539.01
Organism:
Mycobacterium tuberculosis (strain H37Rv)
Description:
P9WQA3
Residue:
344
Sequence:
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
  
Inhibitor
Name:
BDBM96143
Synonyms:
5-methyl-4-(7-methyl-2-imidazo[1,2-a]pyridinyl)isoxazole | 5-methyl-4-(7-methylimidazo[1,2-a]pyridin-2-yl)-1,2-oxazole | 5-methyl-4-(7-methylimidazo[1,2-a]pyridin-2-yl)isoxazole | 7-methyl-2-(5-methyl-4-isoxazolyl)imidazo[1,2-a]pyridine | MLS000540944 | SMR000126002 | cid_1488778
Type:
Small organic molecule
Emp. Form.:
C12H11N3O
Mol. Mass.:
213.2352
SMILES:
Cc1oncc1-c1cn2ccc(C)cc2n1
Structure:
Search PDB for entries with ligand similarity: