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TargetFructose-1,6-bisphosphate aldolase (FBA)
LigandBDBM96181
Substrate/Competitorn/a
IC50>369.97±n/a nM
Citation PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis PubChem Bioassay(2013)[AID]
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Fructose-1,6-bisphosphate aldolase (FBA)
Name:Fructose-1,6-bisphosphate aldolase (FBA)
Synonyms:FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba
Type:Protein
Mol. Mass.:36539.01
Organism:Mycobacterium tuberculosis (strain H37Rv)
Description:P9WQA3
Residue:344
Sequence:
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFG
SGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKG
GNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKL
YTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGL
PADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLK
VDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
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  Blast E-value cutoff:
BDBM96181
NameBDBM96181
Synonyms:2-(3-ethyl-2-keto-4-methyl-chromen-7-yl)oxyacetamide | 2-(3-ethyl-4-methyl-2-oxidanylidene-chromen-7-yl)oxyethanamide | 2-(3-ethyl-4-methyl-2-oxochromen-7-yl)oxyacetamide | 2-[(3-ethyl-4-methyl-2-oxo-1-benzopyran-7-yl)oxy]acetamide | 2-[(3-ethyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide | MLS000088215 | SMR000072456 | cid_889783
TypeSmall organic molecule
Emp. Form.C14H15NO4
Mol. Mass.261.2732
SMILESCCc1c(C)c2ccc(OCC(N)=O)cc2oc1=O
Structure
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n/a