Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM90863
Substrate
n/a
IC50
>118502±n/a nM
Citation
 PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2013)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM90863
Synonyms:
4-methoxy-N-[(salicyloylamino)thiocarbamoyl]benzamide | MLS001210664 | N-[N'-(2-Hydroxy-benzoyl)-hydrazinocarbothioyl]-4-methoxy-benzamide | N-[[(2-hydroxybenzoyl)amino]carbamothioyl]-4-methoxybenzamide | N-[[(2-hydroxyphenyl)carbonylamino]carbamothioyl]-4-methoxy-benzamide | N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-4-methoxybenzamide | SMR000516925 | cid_1933277
Type:
Small organic molecule
Emp. Form.:
C16H15N3O4S
Mol. Mass.:
345.373
SMILES:
COc1ccc(cc1)C(=O)NC(=S)NNC(=O)c1ccccc1O
Structure:
Search PDB for entries with ligand similarity: