Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM96324
Substrate
n/a
IC50
>10455±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM96324
Synonyms:
2-[2-[oxo-(2-thiophen-2-yl-4-quinolinyl)methyl]imino-6-sulfamoyl-1,3-benzothiazol-3-yl]acetic acid methyl ester | 2-[6-sulfamoyl-2-[2-(2-thienyl)quinoline-4-carbonyl]imino-1,3-benzothiazol-3-yl]acetic acid methyl ester | MLS000697121 | SMR000237888 | cid_5069788 | methyl 2-[6-sulfamoyl-2-(2-thiophen-2-ylquinolin-4-yl)carbonylimino-1,3-benzothiazol-3-yl]ethanoate | methyl 2-[6-sulfamoyl-2-(2-thiophen-2-ylquinoline-4-carbonyl)imino-1,3-benzothiazol-3-yl]acetate
Type:
Small organic molecule
Emp. Form.:
C24H18N4O5S3
Mol. Mass.:
538.619
SMILES:
COC(=O)Cn1c2ccc(cc2s\c1=N/C(=O)c1cc(nc2ccccc12)-c1cccs1)S(N)(=O)=O
Structure:
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