Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM96356
Substrate
n/a
IC50
>94047±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM96356
Synonyms:
4-Hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid N'-(2-chloro-acetyl)-hydrazide | MLS000777624 | N'-(2-chloranylethanoyl)-4-oxidanyl-2-oxidanylidene-1H-quinoline-3-carbohydrazide | N'-(2-chloro-1-oxoethyl)-4-hydroxy-2-oxo-1H-quinoline-3-carbohydrazide | N'-(2-chloroacetyl)-4-hydroxy-2-keto-1H-quinoline-3-carbohydrazide | N'-(2-chloroacetyl)-4-hydroxy-2-oxo-1H-quinoline-3-carbohydrazide | SMR000414018 | cid_54679578
Type:
Small organic molecule
Emp. Form.:
C12H10ClN3O4
Mol. Mass.:
295.679
SMILES:
Oc1c(C(=O)NNC(=O)CCl)c(=O)[nH]c2ccccc12
Structure:
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