Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM58610
Substrate
n/a
IC50
>94027±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM58610
Synonyms:
MLS001219939 | N-[(p-anisoylamino)thiocarbamoyl]thiophene-2-carboxamide | N-[[(4-methoxybenzoyl)amino]carbamothioyl]thiophene-2-carboxamide | N-[[(4-methoxyphenyl)carbonylamino]carbamothioyl]thiophene-2-carboxamide | N-[[[(4-methoxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-thiophenecarboxamide | SMR000608467 | Thiophene-2-carboxylic acid [N'-(4-methoxy-benzoyl)-hydrazinocarbothioyl]-amide | cid_1933044
Type:
Small organic molecule
Emp. Form.:
C14H13N3O3S2
Mol. Mass.:
335.401
SMILES:
COc1ccc(cc1)C(=O)NNC(=S)NC(=O)c1cccs1
Structure:
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