Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM89224
Substrate
n/a
IC50
39120±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM89224
Synonyms:
6-(2-furanyl)-[1,2,4]triazolo[4,3-a]pyridine | 6-(2-furyl)-[1,2,4]triazolo[4,3-a]pyridine | 6-(furan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine | MLS003124514 | SMR001285942 | cid_49789308
Type:
Small organic molecule
Emp. Form.:
C10H7N3O
Mol. Mass.:
185.1821
SMILES:
c1coc(c1)-c1ccc2nncn2c1
Structure:
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