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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96649
Substrate
n/a
EC50
11651±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96649
Synonyms:
1-(2,6-dichlorophenoxy)-3-(1,2,3,4-tetrahydronaphthalen-1-ylamino)-2-propanol;oxalic acid | 1-(2,6-dichlorophenoxy)-3-(1,2,3,4-tetrahydronaphthalen-1-ylamino)propan-2-ol;oxalic acid | 1-(2,6-dichlorophenoxy)-3-(tetralin-1-ylamino)propan-2-ol;oxalic acid | 1-[2,6-bis(chloranyl)phenoxy]-3-(1,2,3,4-tetrahydronaphthalen-1-ylamino)propan-2-ol;ethanedioic acid | MLS000334339 | SMR000249097 | cid_15944923
Type:
Small organic molecule
Emp. Form.:
C19H21Cl2NO2
Mol. Mass.:
366.282
SMILES:
OC(CNC1CCCc2ccccc12)COc1c(Cl)cccc1Cl
Structure:
Search PDB for entries with ligand similarity: