Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96866
Substrate
n/a
EC50
>29883±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96866
Synonyms:
(2S)-1-[(2S)-2-[[2,4-bis(fluoranyl)phenyl]sulfonylamino]-2-phenyl-ethanoyl]-N-[2-(2-chlorophenyl)ethyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(2,4-difluorophenyl)sulfonylamino]-1-oxo-2-phenylethyl]-2-pyrrolidinecarboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(2,4-difluorophenyl)sulfonylamino]-2-phenyl-acetyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(2,4-difluorophenyl)sulfonylamino]-2-phenylacetyl]pyrrolidine-2-carboxamide | MLS003777886 | SMR002440866 | cid_53361882
Type:
Small organic molecule
Emp. Form.:
C27H26ClF2N3O4S
Mol. Mass.:
562.028
SMILES:
Fc1ccc(c(F)c1)S(=O)(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1Cl)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: