Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96736
Substrate
n/a
IC50
372.87±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96736
Synonyms:
1-[6-(7-chloranylquinazolin-4-yl)oxypyridin-3-yl]-3-(4-fluorophenyl)urea | 1-[6-(7-chloroquinazolin-4-yl)oxy-3-pyridyl]-3-(4-fluorophenyl)urea | 1-[6-(7-chloroquinazolin-4-yl)oxypyridin-3-yl]-3-(4-fluorophenyl)urea | 1-[6-[(7-chloro-4-quinazolinyl)oxy]-3-pyridinyl]-3-(4-fluorophenyl)urea | MLS000860602 | N-{6-[(7-chloro-4-quinazolinyl)oxy]-3-pyridinyl}-N'-(4-fluorophenyl)urea | SMR000458686 | cid_2814119
Type:
Small organic molecule
Emp. Form.:
C20H13ClFN5O2
Mol. Mass.:
409.801
SMILES:
Fc1ccc(NC(=O)Nc2ccc(Oc3ncnc4cc(Cl)ccc34)nc2)cc1
Structure:
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