Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97105
Substrate
n/a
IC50
>29910±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97105
Synonyms:
2-(1-adamantyl)-4-chloranyl-5-(oxolan-2-ylmethylamino)pyridazin-3-one | 2-(1-adamantyl)-4-chloro-5-(2-oxolanylmethylamino)-3-pyridazinone | 2-(1-adamantyl)-4-chloro-5-(oxolan-2-ylmethylamino)pyridazin-3-one | 2-(1-adamantyl)-4-chloro-5-(tetrahydrofurfurylamino)pyridazin-3-one | 2-(1-adamantyl)-4-chloro-5-[(tetrahydrofuran-2-ylmethyl)amino]pyridazin-3(2H)-one | MLS000730667 | SMR000308943 | cid_16193721
Type:
Small organic molecule
Emp. Form.:
C19H26ClN3O2
Mol. Mass.:
363.882
SMILES:
[H]C12CC3([H])CC([H])(C1)CC(C2)(C3)n1ncc(NCC2CCCO2)c(Cl)c1=O |TLB:8:1:12:6.9.5,8:6:12:1.11.2,THB:5:6:11:3.12.2|
Structure:
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