Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97158
Substrate
n/a
IC50
449.14±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97158
Synonyms:
MLS001156746 | N-[3-(diethylsulfamoyl)-4-methyl-phenyl]-2-(3-morpholinosulfonylanilino)acetamide | N-[3-(diethylsulfamoyl)-4-methyl-phenyl]-2-[(3-morpholin-4-ylsulfonylphenyl)amino]ethanamide | N-[3-(diethylsulfamoyl)-4-methylphenyl]-2-(3-morpholin-4-ylsulfonylanilino)acetamide | N-[3-(diethylsulfamoyl)-4-methylphenyl]-2-[3-(4-morpholinylsulfonyl)anilino]acetamide | SMR000712351 | cid_24980848
Type:
Small organic molecule
Emp. Form.:
C23H32N4O6S2
Mol. Mass.:
524.653
SMILES:
CCN(CC)S(=O)(=O)c1cc(NC(=O)CNc2cccc(c2)S(=O)(=O)N2CCOCC2)ccc1C
Structure:
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