Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97186
Substrate
n/a
IC50
400.33±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97186
Synonyms:
2-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-N-(4-phenoxyphenyl)-4-thiazolecarboxamide | 2-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-N-(4-phenoxyphenyl)-1,3-thiazole-4-carboxamide | 2-[(2R,4S,5R)-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]-N-(4-phenoxyphenyl)thiazole-4-carboxamide | 2-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-N-(4-phenoxyphenyl)-1,3-thiazole-4-carboxamide | MLS003119103 | SMR001272583 | cid_49795269
Type:
Small organic molecule
Emp. Form.:
C21H20N2O5S
Mol. Mass.:
412.459
SMILES:
OC[C@H]1O[C@H](C[C@@H]1O)c1nc(cs1)C(=O)Nc1ccc(Oc2ccccc2)cc1
Structure:
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