Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM93942
Substrate
n/a
IC50
17.14±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM93942
Synonyms:
Lyngbyastatin 2 | MLS003235796 | SMR001918760 | cid_51360490
Type:
Small organic molecule
Emp. Form.:
C56H94N6O13
Mol. Mass.:
1059.378
SMILES:
[H][C@@]12CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@]1([H])CCCN1C(=O)[C@H](COC)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)C([C@@H](C)CC)N(C)C(=O)\C=C(\OC)/C(/C)=C\C[C@H](C)[C@@H](C)OC(=O)[C@H](C)[C@H](O)CCC[C@@H](CC)OC2=O |c:56,t:51|
Structure:
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