Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM97297
Substrate
n/a
IC50
>277.86±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM97297
Synonyms:
(3-fluoranyl-4-methoxy-phenyl)methyl 2-morpholin-4-yl-5-nitro-benzoate | (3-fluoro-4-methoxyphenyl)methyl 2-morpholin-4-yl-5-nitrobenzoate | 2-(4-morpholinyl)-5-nitrobenzoic acid (3-fluoro-4-methoxyphenyl)methyl ester | 2-morpholino-5-nitro-benzoic acid (3-fluoro-4-methoxy-benzyl) ester | MLS001141660 | SMR000715572 | cid_7404199
Type:
Small organic molecule
Emp. Form.:
C19H19FN2O6
Mol. Mass.:
390.3624
SMILES:
COc1ccc(COC(=O)c2cc(ccc2N2CCOCC2)[N+]([O-])=O)cc1F
Structure:
Search PDB for entries with ligand similarity: