Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM84342
Substrate
n/a
IC50
>67574±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM84342
Synonyms:
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol | 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1 | 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride | 4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride | 4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride | DL-ADRENALINE HYDROCHLORIDE | EPINEPHRINE | EPINEPHRINE,(+) | MLS001333244 | SMR000058236 | cid_5924
Type:
Small organic molecule
Emp. Form.:
C9H13NO3
Mol. Mass.:
183.2044
SMILES:
CNCC(O)c1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: