Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM97339
Substrate
n/a
IC50
>92.67±n/a nM
Citation
PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
Inhibitor
Name:
BDBM97339
Synonyms:
2-[2-(1,3-benzodioxol-5-yl)ethenyl]-1,3-benzoxazole | 2-[2-(1,3-benzodioxol-5-yl)vinyl]-1,3-benzoxazole | Benzoxazole, 2-[2-(1,3-benzodioxol-5-yl)ethenyl]-, (Z)- | MLS003106874 | SMR001821759 | cid_300942
Type:
Small organic molecule
Emp. Form.:
C16H11NO3
Mol. Mass.:
265.2634
SMILES:
C1Oc2ccc(C=Cc3nc4ccccc4o3)cc2O1
Structure:
