Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM97466
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
277.15±n/a K
Ki
4.05±0.0 nM
Comments
extracted
Citation
 Barman, S; Baumgartner, RA Method of reducing intraocular pressure in humans US Patent  US8470800 Publication Date 6/25/2013 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM97466
Synonyms:
US8470800, C
Type:
Small organic molecule
Emp. Form.:
C15H20N5NaO7S
Mol. Mass.:
437.403
SMILES:
O[C@@H]1[C@@H](COS(=O)(=O)O[Na])O[C@H]([C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12 |r|
Structure:
Search PDB for entries with ligand similarity: