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Targetidh2 r140q 16 hr nadph/ nadp
LigandBDBM280145
Substrate/Competitorn/a
Meas. Tech.In Vitro Assays for IDH2m R140Q Inhibitors
pH7.5±n/a
Temperature298.15±n/a K
IC50 75±n/a nM
Commentsextracted
Citation Konteatis, ZDPopovici-Muller, JTravins, JMZahler, RCai, ZZhou, D Therapeutically active compounds and their methods of use US Patent US10028961 Publication Date 7/24/2018
More Info.:Get all data from this article,  Assay Method
 
idh2 r140q 16 hr nadph/ nadp
BDBM280145
NameBDBM280145
Synonyms:US10028961, Compound 298 | US10172864, Compound 298
TypeSmall organic molecule
Emp. Form.C18H17F5N8
Mol. Mass.440.3732
SMILESCC(C)Nc1nc(Nc2ccnc(c2)C(C)(F)F)nc(n1)-c1nccc(n1)C(F)(F)F
Structure
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