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Target
Serine/threonine-protein kinase pim-1
Ligand
BDBM50299248
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
7.8e+2±n/a nM
Citation
 Anizon, F; Moreau, P; Prudhomme, M; Cohen, P; Aboab, B; Akue-Gedu, R; Rossignol, E Pyrrolo[2,3-a] carbazoles and use thereof as PIM kinase inhibitors US Patent  US8481586 Publication Date 7/9/2013 
Target
Name:
Serine/threonine-protein kinase pim-1
Synonyms:
PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1)
Type:
Protein
Mol. Mass.:
35681.82
Organism:
Homo sapiens (Human)
Description:
P11309
Residue:
313
Sequence:
MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK
  
Inhibitor
Name:
BDBM50299248
Synonyms:
1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide | CHEMBL573176 | US8481586, 5
Type:
Small organic molecule
Emp. Form.:
C15H11N3O
Mol. Mass.:
249.2673
SMILES:
NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21
Structure:
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