Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM98179
Substrate
n/a
Meas. Tech.
In Vitro Binding Assay
Ki
5.7±0.0 nM
Citation
 Kassiou, M; James, ML; Luus, CA Translocator protein ligands US Patent  US8492379 Publication Date 7/23/2013 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM98179
Synonyms:
US8492379, 56
Type:
Small organic molecule
Emp. Form.:
C23H25ClN2O3
Mol. Mass.:
412.909
SMILES:
CCN(CC)C(=O)C(Oc1ccc(Cl)cc1-n1cccc1)c1ccc(OC)cc1
Structure:
Search PDB for entries with ligand similarity: