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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine kinase non-receptor protein 2 | ||
| Ligand | BDBM98199 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | AlphaScreen Assay | ||
| IC50 | 152.6± 0 nM | ||
| Citation |  Crew, AP; Jin, M; Kadalbajoo, M; Kleinberg, A; Mulvihill, MJ; Wang, J Substituted imidazopyr- and imidazotri-azines US Patent US8481733 Publication Date 7/9/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine kinase non-receptor protein 2 | |||
| Name: | Tyrosine kinase non-receptor protein 2 | ||
| Synonyms: | Activated CDC42 kinase 1 (ACK-1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 114577.86 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q07912 | ||
| Residue: | 1038 | ||
| Sequence: |
| ||
| BDBM98199 | |||
| Name | BDBM98199 | ||
| Synonyms: | US8481733, 10 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H20N4O2 | ||
| Mol. Mass. | 372.4198 | ||
| SMILES | Nc1nccn2c(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1C[C@H](O)C1 |r,wU:23.26,25.29,(-5.14,3.1,;-5.14,1.56,;-6.48,.79,;-6.48,-.75,;-5.14,-1.52,;-3.81,-.75,;-2.34,-1.23,;-1.44,.02,;-2.34,1.26,;-1.25,2.35,;.23,1.95,;1.32,3.04,;.92,4.53,;2.01,5.62,;3.5,5.22,;3.9,3.73,;5.39,3.33,;6.48,4.42,;6.08,5.91,;4.59,6.31,;-.56,4.93,;-1.65,3.84,;-3.81,.79,;-1.94,-2.72,;-2.71,-4.05,;-1.38,-4.82,;-.98,-6.31,;-.61,-3.49,)| | ||
| Structure |  | ||
| n/a | |||