Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM98594
Substrate
n/a
Meas. Tech.
Enzyme Assay
Temperature
297.15±0 K
Ki
350±0.0 nM
Citation
 Stuerzebecher, J; Steinmetzer, T; Schweinitz, A Urokinase inhibitors, production and use thereof US Patent  US8476306 Publication Date 7/2/2013 
Target
Name:
Serine protease 1
Synonyms:
PTRYI | Prss1 | RATPTRYI | TRY1_RAT | Trp1 | Try1 | Tryp1 | Trypsin
Type:
Protein
Mol. Mass.:
25951.67
Organism:
Rattus norvegicus
Description:
P00762
Residue:
246
Sequence:
MSALLILALVGAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGDEQFINAAKIIKHPNYSSWTLNNDIMLIKLSSPVKLNARVAPVALPSACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAYPGEITSSMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALPDNPGVYTKVCNFVGWIQDTIAAN
  
Inhibitor
Name:
BDBM98594
Synonyms:
(2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]-2-[(4-chlorophenyl)methylsulfonylamino]-3-hydroxy-propanamide | US8476306, 6.20
Type:
Small organic molecule
Emp. Form.:
C20H24ClN5O5S
Mol. Mass.:
481.953
SMILES:
NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(Cl)cc2)cc1
Structure:
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