Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM98602
Substrate
n/a
Meas. Tech.
Enzyme Assay
Temperature
297.15±0 K
Ki
180±0.0 nM
Citation
 Stuerzebecher, J; Steinmetzer, T; Schweinitz, A Urokinase inhibitors, production and use thereof US Patent  US8476306 Publication Date 7/2/2013 
Target
Name:
Serine protease 1
Synonyms:
PTRYI | Prss1 | RATPTRYI | TRY1_RAT | Trp1 | Try1 | Tryp1 | Trypsin
Type:
Protein
Mol. Mass.:
25951.67
Organism:
Rattus norvegicus
Description:
P00762
Residue:
246
Sequence:
MSALLILALVGAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGDEQFINAAKIIKHPNYSSWTLNNDIMLIKLSSPVKLNARVAPVALPSACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAYPGEITSSMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALPDNPGVYTKVCNFVGWIQDTIAAN
  
Inhibitor
Name:
BDBM98602
Synonyms:
3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonylamino)propanoyl]amino]acetyl]amino]phenyl]-4-methoxy-benzamide | US8476306, 11
Type:
Small organic molecule
Emp. Form.:
C20H26N6O4S
Mol. Mass.:
446.523
SMILES:
NC(CNS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1ccc(cc1)C(N)=N
Structure:
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