Reaction Details Report a problem with these data
Target
Adenosine receptor A2
Ligand
BDBM99199
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
5540±0.0 nM
Citation
 Jagtap, P Adenosine compounds and their use thereof US Patent  US8501708 Publication Date 8/6/2013 
Target
Name:
Adenosine receptor A2
Synonyms:
Adenosine A2a receptor
Type:
Protein
Mol. Mass.:
44661.95
Organism:
Oryctolagus cuniculus (rabbit)
Description:
XP_002722612 (sequence modified)
Residue:
409
Sequence:
MGSWVYITVELAIAVLAVLGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPREGRNHSQGCGAGQVACLFEDVVPMNYMVYYNFFACVLLPLLLMLGIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTLFCPECSHAPLWLMYLAIVLSHSNSVVNPFIYAYRIREFRQTFRKIIRSHVLRRQDPFKAGGTSARALAAHGSDGEHVSLRLNGHPPGLWANGSAPHPQRRPNGYALGLGSTGGARASHRDVSLPDVELLGQERKSMCPESPGLEEPLAQDGAGVS
  
Inhibitor
Name:
BDBM99199
Synonyms:
US8501708, 19
Type:
Small organic molecule
Emp. Form.:
C22H26FN5O5
Mol. Mass.:
459.4707
SMILES:
OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC3CCC[C@@H]3OCc3ccc(F)cc3)ncnc12 |r|
Structure:
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