Reaction Details Report a problem with these data
Target
Reverse transcriptase protein
Ligand
BDBM2115
Substrate
n/a
Meas. Tech.
Enzyme Inhibition Assay
IC50
4390±n/a nM
Citation
 Bode, ML; Rousseau, AL; Gravestock, D; Moleele, SS; Van Der Westhuyzen, CW Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors US Patent  US8501767 Publication Date 8/6/2013 
Target
Name:
Reverse transcriptase protein
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
30157.99
Organism:
Human immunodeficiency virus 1
Description:
Q9WJP9
Residue:
259
Sequence:
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKNSKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNRKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQK
  
Inhibitor
Name:
BDBM2115
Synonyms:
MLB133-641A | US8501787, 8
Type:
n/a
Emp. Form.:
C19H20ClN3
Mol. Mass.:
325.835
SMILES:
Clc1ccccc1-c1nc2ccccn2c1NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: