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Target
Kallikrein-7
Ligand
BDBM100049
Substrate
n/a
EC50
3188±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100049
Synonyms:
3-(3,5-dimethylphenoxy)-4-oxo-4H-chromen-7-yl propyl carbonate | MLS000585100 | SMR000203863 | [3-(3,5-dimethylphenoxy)-4-oxidanylidene-chromen-7-yl] propyl carbonate | [3-(3,5-dimethylphenoxy)-4-oxochromen-7-yl] propyl carbonate | carbonic acid [3-(3,5-dimethylphenoxy)-4-keto-chromen-7-yl] propyl ester | carbonic acid [3-(3,5-dimethylphenoxy)-4-oxo-1-benzopyran-7-yl] propyl ester | cid_1561320
Type:
Small organic molecule
Emp. Form.:
C21H20O6
Mol. Mass.:
368.3799
SMILES:
CCCOC(=O)Oc1ccc2c(c1)occ(Oc1cc(C)cc(C)c1)c2=O
Structure:
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