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Target
Kallikrein-7
Ligand
BDBM100066
Substrate
n/a
EC50
38811±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100066
Synonyms:
MLS000686440 | N-[2-(3,4-dimethoxyphenyl)-4-keto-1,2-dihydroquinazolin-3-yl]methanesulfonamide | N-[2-(3,4-dimethoxyphenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]methanesulfonamide | N-[2-(3,4-dimethoxyphenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]methanesulfonamide | N-[2-(3,4-dimethoxyphenyl)-4-oxo-1,4-dihydroquinazolin-3(2H)-yl]methanesulfonamide | SMR000313283 | cid_3267339
Type:
Small organic molecule
Emp. Form.:
C17H19N3O5S
Mol. Mass.:
377.415
SMILES:
COc1ccc(cc1OC)C1Nc2ccccc2C(=O)N1NS(C)(=O)=O
Structure:
Search PDB for entries with ligand similarity: