Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM82911
Substrate
n/a
EC50
>7718±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM82911
Synonyms:
2-(2-furanyl)-6-(2-propan-2-yloxyethoxy)-1-benzopyran-4-one | 2-(2-furyl)-6-(2-isopropoxyethoxy)-4H-chromen-4-one | 2-(2-furyl)-6-(2-isopropoxyethoxy)chromone | 2-(furan-2-yl)-6-(2-propan-2-yloxyethoxy)chromen-4-one | MLS001163009 | SMR000498532 | cid_1579310
Type:
Small organic molecule
Emp. Form.:
C18H18O5
Mol. Mass.:
314.3325
SMILES:
CC(C)OCCOc1ccc2oc(cc(=O)c2c1)-c1ccco1
Structure:
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