Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100143
Substrate
n/a
EC50
7569±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100143
Synonyms:
MLS001035725 | N-[4-[2-(2-methoxyphenyl)ethanoylamino]phenyl]thiophene-2-carboxamide | N-[4-[[2-(2-methoxyphenyl)-1-oxoethyl]amino]phenyl]-2-thiophenecarboxamide | N-[4-[[2-(2-methoxyphenyl)acetyl]amino]phenyl]thiophene-2-carboxamide | SMR000666281 | cid_1293625
Type:
Small organic molecule
Emp. Form.:
C20H18N2O3S
Mol. Mass.:
366.434
SMILES:
COc1ccccc1CC(=O)Nc1ccc(NC(=O)c2cccs2)cc1
Structure:
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