Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100194
Substrate
n/a
EC50
>2573±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100194
Synonyms:
3-(3,4-dimethylphenyl)-N-[(2-methoxy-1-naphthalenyl)methylideneamino]-1H-pyrazole-5-carboxamide | 3-(3,4-dimethylphenyl)-N-[(2-methoxy-1-naphthyl)methyleneamino]-1H-pyrazole-5-carboxamide | 3-(3,4-dimethylphenyl)-N-[(2-methoxynaphthalen-1-yl)methylideneamino]-1H-pyrazole-5-carboxamide | MLS003128191 | SMR001836243 | cid_5234558
Type:
Small organic molecule
Emp. Form.:
C24H22N4O2
Mol. Mass.:
398.4571
SMILES:
COc1ccc2ccccc2c1C=NNC(=O)c1cc(n[nH]1)-c1ccc(C)c(C)c1 |w:13.15|
Structure:
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