Reaction Details Report a problem with these data
Target
Vascular endothelial growth factor A
Ligand
BDBM102346
Substrate
n/a
Meas. Tech.
ELISA Assay
IC50
1.9e+4±n/a nM
Citation
 Gardner, JH; Shalwitz, R Prolyl hydroxylase inhibitors US Patent  US8536181 Publication Date 9/17/2013 
Target
Name:
Vascular endothelial growth factor A
Synonyms:
VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor
Type:
Protein
Mol. Mass.:
27063.81
Organism:
Homo sapiens (Human)
Description:
P15692
Residue:
232
Sequence:
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSLPGPHPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
  
Inhibitor
Name:
BDBM102346
Synonyms:
US10562854, No. D14 | US8536181, D14 | US9278930, D14
Type:
Small organic molecule
Emp. Form.:
C21H22ClN5O4S
Mol. Mass.:
475.948
SMILES:
Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCN(CC2)c2ccc(Cl)nn2)c(O)c1=O
Structure:
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