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TargetBradykinin-1 Receptor
LigandBDBM107186
Substrate/Competitorn/a
Meas. Tech.Binding Assay
Ki 17.1± 0 nM
Citation Aebi, JBinggeli, AHertel, CKonkar, AAKuehne, HKuhn, BMaerki, HPWang, H Aryl-benzocycloalkyl amide derivatives US Patent US8592426 Publication Date 11/26/2013
More Info.:Get all data from this article,  Assay Method
 
Bradykinin-1 Receptor
Name:Bradykinin-1 Receptor
Synonyms:n/a
Type:Enzyme
Mol. Mass.:71962.11
Organism:Homo sapiens (Human)
Description:P01042
Residue:644
Sequence:
MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT
EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS
VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN
EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR
IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK
IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW
EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG
KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD
DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE
KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF
NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM107186
NameBDBM107186
Synonyms:US8592426, 35
TypeSmall organic molecule
Emp. Form.C27H22ClF2N5O5
Mol. Mass.569.944
SMILESCOc1cc(on1)C(=O)NC1(CC1)C(=O)NC1CCc2cc(cc(F)c12)-c1cc(Cl)cc(F)c1-c1noc(C)n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a