Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBradykinin-1 Receptor
LigandBDBM107208
Substrate/Competitorn/a
Meas. Tech.Binding Assay
Ki 6.3± 0 nM
Citation Aebi, JBinggeli, AHertel, CKonkar, AAKuehne, HKuhn, BMaerki, HPWang, H Aryl-benzocycloalkyl amide derivatives US Patent US8592426 Publication Date 11/26/2013
More Info.:Get all data from this article,  Assay Method
 
Bradykinin-1 Receptor
Name:Bradykinin-1 Receptor
Synonyms:n/a
Type:Enzyme
Mol. Mass.:71962.11
Organism:Homo sapiens (Human)
Description:P01042
Residue:644
Sequence:
MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT
EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS
VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN
EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR
IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK
IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW
EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG
KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD
DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE
KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF
NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM107208
NameBDBM107208
Synonyms:US8592426, 58
TypeSmall organic molecule
Emp. Form.C25H22ClFN8O3
Mol. Mass.536.945
SMILESCc1cc(on1)C(=O)NC1(CC1)C(=O)NC1CCc2cc(cnc12)-c1cc(Cl)cc(F)c1-c1nnn(C)n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a