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Target
Transcription initiation factor IIA subunit 1
Ligand
BDBM108109
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
13000±0.0 nM
Citation
 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A Trypsin-like serine protease inhibitors, and their preparation and use US Patent  US8598206 Publication Date 12/3/2013 
Target
Name:
Transcription initiation factor IIA subunit 1
Synonyms:
GTF2A1 | TF2A1 | TF2AA_HUMAN | Transcription initiation factor IIA
Type:
Enzyme
Mol. Mass.:
41485.12
Organism:
Homo sapiens (Human)
Description:
P52655
Residue:
376
Sequence:
MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
  
Inhibitor
Name:
BDBM108109
Synonyms:
US8598206, 118 | US8598206, 122
Type:
Small organic molecule
Emp. Form.:
C37H55N7O5S
Mol. Mass.:
709.941
SMILES:
CC(C)C(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 |r|
Structure:
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