Reaction Details Report a problem with these data
Target
Histone H1.0
Ligand
BDBM21398
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
780±0.0 nM
Citation
 Mates, S; Fienberg, A; Wennogle, L Methods and compositions for sleep disorders and other disorders US Patent  US8598119 Publication Date 12/3/2013 
Target
Name:
Histone H1.0
Synonyms:
H1-0 | H10_HUMAN | H1F0 | H1FV | Histone H1
Type:
Cell-surface receptors
Mol. Mass.:
20917.09
Organism:
Homo sapiens (Human)
Description:
P07305
Residue:
194
Sequence:
MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
  
Inhibitor
Name:
BDBM21398
Synonyms:
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl) | 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one | CHEMBL54 | CHEMBL545608 | Haloperidol | Haloperidol, 1
Type:
Small organic molecule
Emp. Form.:
C21H23ClFNO2
Mol. Mass.:
375.864
SMILES:
OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Structure:
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