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Target
SGLT1 protein
Ligand
BDBM109277
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
2600±0.0 nM
Citation
 Yang, F; Tang, PC; Dong, Q; Tu, W; Fan, J; Guan, D; Shen, G; Wang, Y; Yuan, J; Zhang, L C-aryl glucoside derivatives, preparation process and pharmaceutical use thereof US Patent  US8609622 Publication Date 12/17/2013 
Target
Name:
SGLT1 protein
Synonyms:
Q9QXI6_MOUSE | SGLT1 protein | Sglt1 | Slc5a1 | Solute carrier family 5 (Sodium/glucose cotransporter), member 1 | Uncharacterized protein | sodium-dependent glucose cotransporter 1 (SGLT1)
Type:
Protein
Mol. Mass.:
73320.01
Organism:
Mus musculus (Mouse)
Description:
Q9QXI6
Residue:
665
Sequence:
MDSSTLSPAVTATDAPIPSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVVLGWIFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPRADSFHIFRDPITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFVISVITILIISFLTKPIPDVHLYRLCWSLRNSKEERIDLDAGEEEDIPEDSKDTIEIDTEAPQKKKGCFRRAYDLFCGLDQDKGPKMTKEEEEAMKMKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA
  
Inhibitor
Name:
BDBM109277
Synonyms:
US8609622, 4
Type:
Small organic molecule
Emp. Form.:
C22H24ClFO7
Mol. Mass.:
454.873
SMILES:
CCOc1ccc(Cc2cc(ccc2Cl)C23OC[C@@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1F |r|
Structure:
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