Reaction Details Report a problem with these data
Target
Cytidine deaminase
Ligand
BDBM111584
Substrate
n/a
Meas. Tech.
Enzyme Assay
pH
7.4±n/a
IC50
5000±2000 nM
Comments
extracted
Citation
 Hamilton, GS; Tsukamoto, T; Ferraris, DV; Duvall, B; Lapidus, R Certain compounds, compositions and methods US Patent  US8618075 Publication Date 12/31/2013 
Target
Name:
Cytidine deaminase
Synonyms:
CDA | CDD | CDD_HUMAN | Cytidine deaminase | Cytidine deaminase (CDA)
Type:
Ezyme
Mol. Mass.:
16185.04
Organism:
Homo sapiens (Human)
Description:
P32320
Residue:
146
Sequence:
MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ
  
Inhibitor
Name:
BDBM111584
Synonyms:
US8618075, 2b
Type:
Small organic molecule
Emp. Form.:
C9H15FN2O5
Mol. Mass.:
250.2242
SMILES:
OC[C@H]1OC([C@@H](F)[C@@H]1O)N1CC[C@H](O)NC1=O |r|
Structure:
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