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Target
Fibrinogen beta chain [164-491]
Ligand
BDBM32008
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer
IC50
83289±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay (2013)[AID] 
Target
Name:
Fibrinogen beta chain [164-491]
Synonyms:
Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37647.12
Organism:
Homo sapiens (Human)
Description:
gi_28373962
Residue:
328
Sequence:
DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQQ
  
Inhibitor
Name:
BDBM32008
Synonyms:
1-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine;hydrochloride | 4-aminopentyl-(6-methoxy-8-quinolyl)amine;hydrochloride | MLS000073645 | N*1*-(6-Methoxy-quinolin-8-yl)-pentane-1,4-diamine | N1-(6-methoxy-8-quinolinyl)pentane-1,4-diamine;hydrochloride | N1-(6-methoxyquinolin-8-yl)pentane-1,4-diamine;hydrochloride | SMR000008699 | cid_6603104
Type:
Small organic molecule
Emp. Form.:
C15H21N3O
Mol. Mass.:
259.3467
SMILES:
COc1cc(NCCCC(C)N)c2ncccc2c1
Structure:
Search PDB for entries with ligand similarity: