Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, liver [T94A]
Ligand
BDBM50085042
Substrate
n/a
Meas. Tech.
ANS Fluorescence Displacement Assay
Ki
15± 1 nM
Citation
 Martin, GG; McIntosh, AL; Huang, H; Gupta, S; Atshaves, BP; Landrock, KK; Landrock, D; Kier, AB; Schroeder, F The human liver fatty acid binding protein T94A variant alters the structure, stability, and interaction with fibrates. Biochemistry 52:9347-57 (2013) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, liver [T94A]
Synonyms:
FABP1 | FABPL | FABPL_HUMAN | Liver fatty acid binding protein (human L-FABP T94A)
Type:
Protein
Mol. Mass.:
14178.70
Organism:
Homo sapiens (Human)
Description:
human L-FABP mutant T94A
Residue:
127
Sequence:
MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTAFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI
  
Inhibitor
Name:
BDBM50085042
Synonyms:
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester | CHEMBL672 | FENOFIBRATE | FNF | Fenofibric acid | Finofibrate | Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate | Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate | Lipantil (TN) | Procetofen | Tricor (TN) | propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
Type:
Small organic molecule
Emp. Form.:
C20H21ClO4
Mol. Mass.:
360.831
SMILES:
CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1
Structure:
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