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Target
Cathepsin H
Ligand
BDBM120827
Substrate
n/a
Meas. Tech.
Enzymatic activity assay
pH
6±n/a
Temperature
310.15±n/a K
Ki
0.963±0.096 nM
Comments
extracted
Citation
 Raghav, N; Garg, S N-formylpyrazolines and N-benzoylpyrazolines as novel inhibitors of mammalian cathepsin B and cathepsin H. Bioorg Chem 57:43-50 (2014) [PubMed]  Article 
Target
Name:
Cathepsin H
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
37394.24
Organism:
Capra hircus (Goat)
Description:
A0A060INS8
Residue:
335
Sequence:
MWAVLPLLCAGAWLLGAPACGAAELAVNSLEKFHFQSWMVQHQKKYSSEEYHHRLQVFASNLREINAHNARNHTFKMGLNQFSDMSFAELKRKYLWSEPQNCSATKSNYLRGTGPYPPSMDWREKGNFVTPVKNQGSCGSCWTFSTTGALESAVAIATGKLPFLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYRGQDGDCKYQPSKAIAFVKDVANITLNDEEAMVEAVALYNPVSFAFEVTADFMMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEEKGIPYWIVKNSWGPHWGMKGYFLIERGKNMCGLAACASFPIPLV
  
Inhibitor
Name:
BDBM120827
Synonyms:
N-formyl-5-(-2'-nitrophenyl)-3-phenylpyrazoline (1h)
Type:
Small organic molecule
Emp. Form.:
C16H13N3O3
Mol. Mass.:
295.2927
SMILES:
[O-][N+](=O)c1ccccc1C1CC(=NN1C=O)c1ccccc1 |c:12|
Structure:
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