Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM122380
Substrate
n/a
Meas. Tech.
Binding assay
Temperature
277.15±n/a K
Ki
0.4±n/a nM
Comments
extracted
Citation
 Galley, G; Goergler, A; Groebke Zbinden, K; Norcross, R 4,5-dihydro-oxazol-2yl derivatives US Patent  US8729113 Publication Date 5/20/2014 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM122380
Synonyms:
US8729113, 136
Type:
Small organic molecule
Emp. Form.:
C19H20N2O4
Mol. Mass.:
340.3731
SMILES:
NC1=N[C@@H](CCOc2cccc(c2)C(=O)OCc2ccccc2)CO1 |r,t:1|
Structure:
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